The researchers randomly assigned 8,506 women to receive a combination of estrogen (0.625 milligrams of conjugated equine estrogens per day) plus progesterone (2.5 milligrams of medroxyprogesterone acetate per day), while 8,102 took a placebo. Garnet Anderson, Chu Chen, all of the Public Health Sciences Division, studied 16,608 post-menopausal women who participated in the Women’s Health Initiative clinical trial, beginning in 1993 through 1998. Rowan Chlebowski, of the Los Angeles Biomedical Research Institute at Harbor–UCLA Medical Center, and colleagues, including McTiernan and co-authors Drs. The increased risk of abnormal mammograms and breast biopsies can affect women economically and emotionally,” said co-author Dr. “This study provides additional information for women on the health effects of combined hormone therapy. 25 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. Viruses, Vaccines and Infectious DiseasesĬombined hormone therapy appears to increase the risk that women will have abnormal mammograms and breast biopsies and may decrease the effectiveness of both methods for detecting breast cancer, according to a report in the Feb.Institutional Partners & Collaborations.Vaccine and Infectious Disease Division.
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